Queen's Domain bosses

All 21 boss fights in the order you meet them, with in-game Life and attack, the damage type each one is weak to, and where the arena is. Slash, Impact and Pierce matter: a weak-to hit does extra damage, a resisted one barely scratches.

Boss	Life / ATK / weak to	Where and how
Shrine GuardianIsle of Neasied	260 Life, 18 ATK Impact	Endu Shrine: from the Dagger Belt coast cross the short mossy stone causeway over the turquoise water to the single broken arch. Open the gate with the Endu Shrine Gate Key from the bottom of the Crypt.Weak to Impact, so take the Wooden Club. Circle around its committed swing and spend the recovery window on a charged Impact hit.
Dagoom the Sea KingObmuer Temple	1500 Life, 27 ATK no weakness	Obmuer Temple: from the Prison Corridor monument follow the central path into the big cavern. The boss door opens once the three Royal Orbewa Guards are beaten; the Lift Room monument is just past the arena.No physical weakness. Keep moving, air-dash out of poison clouds, whirlpools and water jets, and kill the Toxic Serfs before they crowd the arena; charged Torch fire works when a close opening is unsafe.
Royal Orbewa Guard (Yepo, Erda, Wami)Obmuer Temple	Yepo of the Royal Orbewa Guard: 200 Life, 30 ATK no weakness Erda of the Royal Orbewa Guard: 250 Life, 25 ATK Pierce Wami of the Royal Orbewa Guard: 300 Life, 25 ATK Pierce	In the big cavern past the Prison Corridor monument. Yepo and Erda wait below the drops near the staircase with the Gold Conch Necklace chest; Wami is further on, past the waterfall. All three open Dagoom's door.
Skeletal ExecutionerTower of Knowledge	900 Life, 45 ATK Impact	Tower of Knowledge: once all three beacon gargoyles are lit the Tower door opens, and the Executioner blocks the first interior door. The Foyer monument is in the hall right behind him.Weak to Impact. Circle-strafe the axe swings, leave the whirl immediately, do not chase the leap, and hit with Impact after it lands.
The NecronomiconTower of Knowledge	Necrotic Baphomet: 3000 Life, 31 ATK Impact Necrotic Eye of Balor: 3000 Life, 31 ATK Slash Necrotic Bael: 3000 Life, 31 ATK Pierce	Tower 6F: open the key door near the Storm Gem with the Forbidden Archives Key and run the narrowing archive corridor past the Forbidden Archives monument. The Necronomicon waits at its end; it drops the Gold Duck and Acid Vial.Three forms with different weak types (Baphomet: Impact, Eye of Balor: Slash, Bael: Pierce). Stay at range with charged Azure Torch fire or throwables, back off when the goat form rushes, and swap to the matching weapon.
Poenir & DuenirDeimpo & the Mausoleum	Poenir, Rotten Wings of Despair: 940 Life, 50 ATK no weakness Duenir, Depraved Horns of Agony: 2300 Life, 44 ATK no weakness	Deimpo Mausoleum: the sealed boss passage near Chef Gagi's part of the Mausoleum, past the Deimpo Wing Altar. It opens once all six Puwema sigils are dispelled. King Gius Abraon is beyond.No known weakness. Split them: pressure Poenir (lower life) in short openings and kite Duenir instead of trading with both.
Ancient Besom CutterAncient World	2900 Life, 60 ATK Slash	Ancient World, Scrap Yard island: from the Scrap Yard monument go straight and up the path on the left of the building; drop down and enter the power tower. The Besom Cutter fights you inside.Weak to Slash, resists Pierce. Sidestep the committed frontal swing and punish only in the recovery.
Josami Lord SaijhaAncient World	4000 Life, 75 ATK no weakness	Ancient World, on the way into Siraatsu Castle: fought after the Ancient Besom Cutter and the seal-breaker puzzles. Beating him opens the castle and the Siraatsu Foyer monument.No known weakness. Use range to reposition and take a single short punish window after his committed attack rather than extending a combo.
Duke Obetda & Duchess Ubhaer (Castle Lords)Siraatsu Castle	Duke Obetda: 1200 Life, 109 ATK Slash Duchess Ubhaer: 1700 Life, 82 ATK Impact	Siraatsu Castle, through the palace rooms beyond the Foyer monument. The first of the three fights that unlock the big Foyer door leading to Queen Siraatsu.Obetda is weak to Slash, Ubhaer to Impact. Keep both in view, use the matching weapon on whichever commits, then back out.
Dekanima Ritual Blood (Tauropod & Stalker)Siraatsu Castle	Ritual Blood Tauropod: 400 Life, 72 ATK Impact Ritual Blood Stalker: 350 Life, 103 ATK Pierce	Siraatsu Castle, the second of the three fights that unlock the big Foyer door; reached by the path to the blood pool, with a large red pipe overhead.Tauropod is weak to Impact, Stalker to Pierce. Keep room so they do not overlap.
High Spec Automatons (Drilling Unit X & Besom Cutter Pro)Siraatsu Castle	Drilling Unit X: 1300 Life, 91 ATK Pierce Besom Cutter Pro: 1800 Life, 68 ATK Slash	Siraatsu Castle, the third of the three fights that unlock the big Foyer door, in the castle's machine area after Dekanima Ritual Blood.Drilling Unit X is weak to Pierce, Besom Cutter Pro to Slash. Carry both weapon types and swap targets.
Queen SiraatsuSiraatsu Castle	2600 Life, 60 ATK no weakness	Siraatsu Castle: behind the big door of the Foyer, which opens after the Castle Lords, Dekanima Ritual Blood and the High Spec Automatons. Back up your save before her final choice.No known weakness. Make an ending-lock backup (Backup A) before her choice, stay at range during unsafe patterns, and take short openings.
Enraged Queen SiraatsuSiraatsu Castle	5000 Life, 85 ATK no weakness	Same arena as Queen Siraatsu behind the big Foyer door: she becomes the Enraged Queen as a second phase when you fight her with the True Holy Sword Akunra (Ending 2 route).
Soul of SipehaSiraatsu Castle	9999 Life, 140 ATK no weakness	Same arena as Queen Siraatsu behind the big Foyer door: fight the Queen with Okbujo's Judgement (Ending 3 route) and the Soul of Sipeha appears.
Usunha & Wujomiod (Shrine of Puwema gatekeepers)Verdant Hollow & Temple Puwema	Dragon Lord Usunha: 2900 Life, 115 ATK no weakness Malachite Dragon Wujomiod: 3500 Life, 150 ATK no weakness	Temple of Puwema at the top of Verdant Hollow (right fork uphill from the Crumbling Fortress monument). The tall gate with the round emblem opens once all eight Sipeha statues are lit; the dragons guard the uppermost shrine.No verified weakness. Use the arena to separate them, keep the more aggressive dragon in view, take short punish windows and save healing for overlaps.
Irdunuub, Priestess of JigekiObmuer Temple	1300 Life, 60 ATK no weakness	Jigeki's Temple below Obmuer: at the fishman statue where the Trident lies (by Aganmi's Camp), set the four Ceremonial Stone Tiaras and drop into the pit. Go straight on to the big serpent door; the arena is Muagyo's Congregation.No verified weakness. Keep ranged pressure as she walks in and take one melee opening only after her committed approach.
Gigantic SerfRotting Cavern	1800 Life, 250 ATK no weakness	Rotting Cavern: from the Decaying Great Tree monument go down the slope into the rot lake and wade a little past the ruined building on the front-left. The Gigantic Serf bursts from the water; the Jigeki Key (middle) is in its mouth.
Blood Angel Lords Yuumed & WoyekiForgotten Dungeon	Blood Angel Lord Yuumed: 6000 Life, 160 ATK no weakness Blood Angel Lord Woyeki: 5000 Life, 190 ATK no weakness	Forgotten Dungeon: the red-glowing cave whose cell door you open after Husipo (chests with the Vampire's Mirror and Amulet of the White Branch). Unlock its inner red door with the Blood Angel Josami Key.
Black Skeletal Witch HusipoForgotten Dungeon	3200 Life, 130 ATK Impact	Forgotten Dungeon: from the Cliff Edge monument ride the lift in the house beside it to the top, drop down the hole past the fire pillar and continue. At the corner the witch is in the room on your right.She spawns Cursed Skulls during the fight.
Herald of OkbujoRecord of Sin	9999 Life, 150 ATK no weakness	Record of Sin: at the very top of the Tower of Sin, one floor above the Peak Antechamber monument where the fourth lift stops. Beating it gives the Memento Mirror and grows the vine at the big bridge.
Lost King OjjamaPetrified Garden	4200 Life, 101 ATK no weakness	Petrified Garden: from the Garden Wing Altar fly to the round platform opposite. Ojjama fights you there and drops the Onyx Trident Key used in the garden ritual.